Gene description for H4C2
Gene name H4 clustered histone 2
Gene symbol H4C2
Other names/aliases H4-16
H4/I
H4C1
H4C11
H4C12
H4C13
H4C14
H4C15
H4C16
H4C3
H4C4
H4C5
H4C6
H4C8
H4C9
H4FI
HIST1H4B
Species Homo sapiens
 Experiment description of studies that identified H4C2 in Leukemia cells

1
Experiment ID1248
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 24939845   
OrganismHomo sapiens
Experiment descriptionHuman T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein.
AuthorsJaworski E, Narayanan A, Van Duyne R, Shabbeer-Meyering S, Iordanskiy S, Saifuddin M, Das R, Afonso PV, Sampey GC, Chung M, Popratiloff A, Shrestha B, Sehgal M, Jain P, Vertes A, Mahieux R, Kashanchi F.
Journal name J Biol Chem.
Publication year2014
SampleLeukemia cells
Sample nameCEM - uninfected
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV140028: EV-METRIC:33%

2
Experiment ID1249
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 24939845   
OrganismHomo sapiens
Experiment descriptionHuman T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein.
AuthorsJaworski E, Narayanan A, Van Duyne R, Shabbeer-Meyering S, Iordanskiy S, Saifuddin M, Das R, Afonso PV, Sampey GC, Chung M, Popratiloff A, Shrestha B, Sehgal M, Jain P, Vertes A, Mahieux R, Kashanchi F.
Journal name J Biol Chem.
Publication year2014
SampleLeukemia cells
Sample nameC81 - HTLV-1 infected
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV140028: EV-METRIC:33%

3
Experiment ID1250
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 24939845   
OrganismHomo sapiens
Experiment descriptionHuman T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein.
AuthorsJaworski E, Narayanan A, Van Duyne R, Shabbeer-Meyering S, Iordanskiy S, Saifuddin M, Das R, Afonso PV, Sampey GC, Chung M, Popratiloff A, Shrestha B, Sehgal M, Jain P, Vertes A, Mahieux R, Kashanchi F.
Journal name J Biol Chem.
Publication year2014
SampleLeukemia cells
Sample nameMT2 - HTLV-1 infected
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV140028: EV-METRIC:33%

4
Experiment ID1251
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 24939845   
OrganismHomo sapiens
Experiment descriptionHuman T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein.
AuthorsJaworski E, Narayanan A, Van Duyne R, Shabbeer-Meyering S, Iordanskiy S, Saifuddin M, Das R, Afonso PV, Sampey GC, Chung M, Popratiloff A, Shrestha B, Sehgal M, Jain P, Vertes A, Mahieux R, Kashanchi F.
Journal name J Biol Chem.
Publication year2014
SampleLeukemia cells
Sample nameED-40515 -HTLV-1 infected
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV140028: EV-METRIC:33%

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